Innovative Enhancements
In addition to your treatment, we believe it is important to offer you approaches and technologies that will help you increase your chances of conception. At the clinique ovo, we are proud to offer several technologies that may help you get closer to your goal faster. Here is a list of treatments that may be beneficial to your situation and may be added to your treatment with the approval of your physician. These approaches may increase your chances of conception.

Eggs:

Violet™

Violet™ is a new artificial intelligence-based tool that will help provide clinicians and patients with an informative report assessing the viability of the patient's eggs. This technology is used in elective fertility preservation to assess the chances of each egg before freezing it so that the best egg can be implanted when the patient is ready to use it.

Sperm:

Sperm selection device ZyMōt™

Sperm preparation before treatment such as intrauterine insemination or IVF is an important step in maximizing the quality of sperm used to fertilize eggs. Although originally developed for cases with high sperm DNA fragmentation, sperm selection by ZyMōt™ is gaining more and more evidence in broader indications. Studies show that ZyMōt™ permits the selection of spermatozoa with low DNA fragmentation, but benefits have also been observed in creating more euploid embryos. The pregnancy rate following intrauterine inseminations indicates that inseminations can also benefit from this technology.

Percutaneous epididymal sperm aspiration (PESA)

This technique can be recommended in cases of obstructive azoospermia when spermatozoids are present and mature, but are unable to leave the epididymis. An example of when this may be recommended is when the vas deferens are obstructed (e.g. following a vasectomy) or completely absent.

Testicular Sperm Extraction (TESE)

This procedure is an option for people who lack sperm production in the epididymis due to previous surgery, infection or a congenital defect.

Testicular spermatozoa collection by microsurgery (micro-TESE)

Micro-TESE is the best option for people with non-obstructive azoospermia, those with insufficient sperm production or maturation. This microsurgery technique allows the specialist to identify the areas where sperm is produced.

The Alessio DNA fragmentation test

The Alessio sperm DNA fragmentation test uses fluorescent biomarkers to measure the proportion of sperm with fragmented DNA. The quality of the genetic information carried by the sperm is a determining factor in the development of a viable embryo. Sperm DNA fragmentation corresponds to “breaks” in the sperm’s genetic material that cannot be detected by conventional examinations. A high number of breaks reduces the chances that a pregnancy will be carried to term, and could be the cause of certain fertility problems.

Uterus:

Endometrial biopsy

The process of removing small fragments of the inner lining of the uterus by aspiration to rule out chronic endometritis or other pathologies.

Embryos:

Time Lapse

Traditionally, during an in vitro fertilization (IVF) cycle, the embryos are removed from the incubator once per day for a very limited period of time in order to assess their development. With the Time Lapse technology, the incubator has a camera that takes photos every few minutes from multiple viewpoints in order to build a ‘video’ of the embryo development. This means that, in addition to the embryologist being able to see events that occurred throughout the day and night, the stable environment of the embryo incubator never needs to be disturbed. 

Preimplantation genetic testing (PGT-A & PGT-M)

PGT allows access to the chromosomal and/or genetic content of the embryo before its transfer into the patient's uterus, thanks to a biopsy of a few cells.

 

In the case of advanced maternal age, failed implantations or recurrent fetal losses, PGT-A analysis allows prioritizing the transfer of an embryo without chromosomal abnormalities in order to maximize the pregnancy rate and reduce the risk of miscarriage.

In the case of an inherited genetic condition carried by one or both biological parents, the PGT-M analysis allows the identification of unaffected embryos, and can be combined with the PGT-A.

Once the results are available, the selected embryos are thawed and transferred to the patient's uterus.

Technologies

MATCHER – Electronic Witness System

MATCHER is a witness system that allows the electronic identification of patients, tubes, culture dishes and even vitrification straws.

This witness system is used in the embryology laboratory, the operating room and in private rooms.

Each patient receives an email from clinique ovo the day before their treatment from identification@cliniqueovo.com with a code that must be saved.

On the day of the visit to the clinic, this code will be scanned by the team on site to identify you and all the samples taken will also be identified with a unique code which will be linked to your file. This therefore allows the system to always know which tube or dish we are referring to.

During all future visits relating to a fertility procedure (in vitro fertilization, embryo transfer, insemination) and requiring the manipulation of your samples, this code will be scanned again. The MATCHER system also takes a picture each time we scan to have double validation as well as a recorded proof of processing the correct samples.

The goal of this electronic witness system is to guarantee the traceability of your samples, without any possible doubt.

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